Projects
Selected projects led by Don Perrault, spanning 30+ years of optical engineering for life sciences.
1. Microscopy & Imaging
Microscopy
- High content, super resolution, quantitative phase, hyperspectral, & laser scanning systems.
Genomic Sequencing
- Ultra-high-throughput imaging system for genomic applications.
Surgical Imaging
- Hyperspectral fluorescence-guided cancer detection system.
- High magnification head-mounted surgical display.
2. Flow Cytometry & Microfluidics
Flow Cytometry
- Developed nine commercial flow cytometers.
- Ultra-high-speed industrial jet-in-air sorters.
- Hyperspectral imaging for nano particle detection.
- Extensive experience in flow cytometer automation.
Clinical Cell Therapy
- Clinical grade microfluidic flow cytometer for iPS cell purification.
- Clinical trials (Parkinson's / Spinal Cord Injuries).
- ISO 9001 Certified, Mfg. Class 7 clean room.
Particle Analysis
- Kohler illumination for particle flow imaging.
- High speed imaging systems.
- Custom microscope objective (NA 1.4), flow cytometer.
3. POC Diagnostics
Raman Imaging Spectrometer
- Compact benchtop optical system for pathogen and hazardous materials detection.
PCR
- High-sensitivity, low-cost multi-color fluorescence PCR instruments.
Detection
- Compact, low cost, multi-spectral aerosol detection system.
- Magnetometer (pico-Tesla) quantum entangled NV diamond.
POC Pathogen Detection
- Fluorimeter for use in developing countries.
- AI-based imaging systems for veterinary diagnostics.
4. Custom Lens and Micro Optics Design
Large Format Lens - f/1.0
- 1:1 fluorescence and scatter imaging of microfluidics chip with hyperspectral capabilities.
Micro Lens Array
- Asphere micro lens array for microfluidics chip fluorescent detection.
Micro Mirror Array
- Micro mirror lens array for microfluidics chip fluorescent detection.
Micro Mirror Beam Splitter Array
- Sawtooth beam splitter mirror array for multi-channel microfluidics chip fluorescence excitation.